• Assessment of extracranial metastatic disease in patients with brain metastases: How much effort is needed in the context of evolving survival prediction models? 

      Nieder, Carsten; Mehta, Minesh P.; Guckenberger, Matthias; Gaspar, Laurie E.; Rusthoven, Chad G.; Sahgal, Arjun; Grosu, Anca L.; De Ruysscher, Dirk (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-04)
      Survival prediction models may serve as decision-support tools for clinicians who have to assign the right treatment to each patient, in a manner whereby harmful over- or undertreatment is avoided as much as possible. Current models differ regarding their components, the overall number of components and the weighting of individual components. Some of the components are easy to assess, such as age ...
    • Management of patients with brain metastases from non-small cell lung cancer and adverse prognostic features: multi-national radiation treatment recommendations are heterogeneous 

      Nieder, Carsten; Guckenberger, Matthias; Gaspar, Laurie E.; Rusthoven, Chad G.; De Ruysscher, Dirk; Sahgal, Arjun; Nguyen, Timothy; Grosu, Anca L.; Mehta, Minesh P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-15)
      <p><i>Background - </i>Different management options exist for patients with brain metastases from non-small cell lung cancer (NSCLC), patients whose treatment with whole brain radiotherapy (WBRT) has become more controversial over the last decade. It is not trivial to find the optimal balance of over- versus undertreatment in these patients. Several recent trials, including the randomized QUARTZ ...
    • Preserving the legacy of reirradiation: A narrative review of historical publications 

      Nieder, Carsten; Langendijk, Johannes A.; Guckenberger, Matthias; Grosu, Anca L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-21)
      The purpose of this study is to illustrate the historical development of reirradiation during several decades of the 20th century, in particular between 1920 and 1960. <br> <br> Methods and materials: We chose the format of a narrative review because the historical articles are heterogeneous. No systematic extraction of baseline data, treatment details, or follow-up care was possible in many ...